Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 7/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.51 |
| ▸ | TDP2 | O95551 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6891893 | 0.88 | PNMT (0.51) | PNMTADRA2ALMNAMEN1MAPT | |
| SCHEMBL7863751 | 0.79 | CA9 (0.45) | PNMTADRA2ALMNAMEN1MAPT | |
| SCHEMBL2728137 | 0.79 | CA9 (0.49) | PNMTADRA2ALMNAMEN1MAPT | |
| SCHEMBL30709850 | 0.78 | PNMT (0.65) | PNMTADRA2ALMNAMEN1MAPT | |
| SCHEMBL9483063 | 0.78 | PNMT (0.65) | PNMTADRA2ALMNAMEN1MAPT | |
| SCHEMBL7208521 | 0.77 | PNMT (0.43) | PNMTADRA2ALMNAMEN1MAPT | |
| SCHEMBL987760 | 0.77 | TLR9 (0.79) | PNMTADRA2ALMNAMEN1MAPT | |
| Ammonia Solution, Strong SCHEMBL27905491 | 0.77 | LMNA (0.62) | PNMTADRA2ALMNAMEN1MAPT | |
| SCHEMBL30049268 | 0.77 | TLR9 (0.79) | PNMTADRA2ALMNAMEN1MAPT | |
| SCHEMBL22898464 | 0.76 | PNMT (0.49) | PNMTADRA2ALMNAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1205473-A1 | VESAMICOL PIPERAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |