Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.36 |
| ▸ | CHRNG | P07510 | 3/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14511367 | 1.00 | KDM4E (0.39) | KDM4EALDH1A1MEN1KMT2ASIGMAR1 | |
| SCHEMBL8095277 | 0.97 | — | — | |
| SCHEMBL18669476 | 0.97 | — | — | |
| SCHEMBL21983946 | 0.97 | — | — | |
| SCHEMBL1785534 | 0.95 | ALDH1A1 (0.41) | KDM4EALDH1A1MEN1KMT2ASLC6A9 | |
| Hydrochloric Acid SCHEMBL9615009 | 0.95 | LMNA (0.39) | KDM4EALDH1A1MEN1KMT2AATM | |
| SCHEMBL4939151 | 0.92 | ALDH1A1 (0.42) | KDM4EALDH1A1MEN1KMT2AATM | |
| SCHEMBL500405 | 0.92 | ALDH1A1 (0.42) | KDM4EALDH1A1MEN1KMT2AATM | |
| SCHEMBL30678696 | 0.92 | ALDH1A1 (0.42) | KDM4EALDH1A1MEN1KMT2AATM | |
| SCHEMBL24220960 | 0.92 | SLC6A9 (0.40) | KDM4EALDH1A1MEN1KMT2ASLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0222886-B2 | HEPATOBILIARY NMR CONTRAST AGENTS | GEN HOSPITAL CORP (US) | 2002-05-02 | — | — | EP | disclosed |
| EP-0222886-B1 | HEPATOBILIARY NMR CONTRAST AGENTS | GEN HOSPITAL CORP (US) | 1996-09-25 | — | — | EP | disclosed |