SCHEMBL8370406

SCHEMBL8370406

C=CCCCCC1CCCCCCBC1C1CCCCCCCC1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.30
CHRNA7 P36544 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8585636 0.79
SCHEMBL7539963 0.74 CHRNB2 (0.33) CHRNB2CHRNA7CHRNA4
SCHEMBL7398026 0.67 SIGMAR1 (0.50) CHRNB2CHRNA7CHRNA4
SCHEMBL6318571 0.67 SIGMAR1 (0.50) CHRNB2CHRNA7CHRNA4
SCHEMBL28815681 0.65 SIGMAR1 (0.54)
SCHEMBL9801592 0.65 SIGMAR1 (0.54)
SCHEMBL1162323 0.65 SIGMAR1 (0.54)
SCHEMBL2265010 0.65 CHRNB2 (0.33) CHRNB2CHRNA7CHRNA4
SCHEMBL30143782 0.64 TSHR (0.59) CHRNB2CHRNA7CHRNA4
SCHEMBL23121455 0.63 SIGMAR1 (0.50) CHRNB2CHRNA7CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758657-B1 Addition polymers derived from norbornene-functional monomers GOODRICH CO B F (US) 1999-02-03 EP disclosed
EP-0729480-B1 ADDITION POLYMERS DERIVED FROM NORBORNENE-FUNCTIONAL MONOMERS AND PROCESS THEREFOR GOODRICH CO B F (US) 1999-01-27 EP disclosed
US-5741869-A REACTION MIXTURE FOR FORMING ADDITION POLYMER COMPRISING NORBORNENE-FUNCTIONAL MONOMER, SOLVENT, GROUP 8 METAL-CONTAINING CATALYST SYSTEM, CHAIN TRANSFER AGENT THE B.F. GOODRICH COMPANY (US) 1998-04-21 US disclosed
EP-0758657-A2 Addition polymers derived from norbornene-functional monomers and process therefor The B.F. Goodrich Company (US) 1997-02-19 EP disclosed
US-5571881-A Addition polymers derived from norbornene-functional monomers and process therefor THE B. F. GOODRICH COMPANY (US) 1996-11-05 US disclosed
US-5569730-A HAVING TERMINAL END GROUP DERIVED FROM CHAIN TRANSFER AGENT CONTAINING TERMINAL OLEFINIC DOUBLE BOND THE B. F. GOODRICH COMPANY (US) 1996-10-29 US disclosed
EP-0729480-A1 ADDITION POLYMERS DERIVED FROM NORBORNENE-FUNCTIONAL MONOMERS AND PROCESS THEREFOR The B.F. Goodrich Company (US) 1996-09-04 EP disclosed
WO-1995014048-A9 ADDITION POLYMERS DERIVED FROM NORBORNENE-FUNCTIONAL MONOMERS AND PROCESS THEREFOR 1995-07-27 WO disclosed
WO-1995014048-A1 ADDITION POLYMERS DERIVED FROM NORBORNENE-FUNCTIONAL MONOMERS AND PROCESS THEREFOR THE B.F. GOODRICH COMPANY (US) 1995-05-26 WO disclosed