Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 14/20 | 0.58 |
| ▸ | CTSS | P25774 | 13/20 | 0.57 |
| ▸ | CTSL | P07711 | 11/20 | 0.57 |
| ▸ | CTSB | P07858 | 9/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7486127 | 0.91 | CTSK (0.55) | CTSKCTSSCTSLCTSBNPC1 | |
| SCHEMBL6185770 | 0.90 | CTSK (0.56) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6182464 | 0.86 | CTSK (0.64) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6404499 | 0.85 | CTSK (0.48) | CTSKCTSSCTSLCTSBNPC1 | |
| SCHEMBL7450076 | 0.83 | CTSB (0.54) | CTSKCTSSCTSLCTSBNPC1 | |
| SCHEMBL7450318 | 0.83 | CTSB (0.54) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6185994 | 0.83 | CTSB (0.54) | CTSKCTSSCTSLCTSBNPC1 | |
| SCHEMBL6184402 | 0.83 | CTSK (0.61) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7507757 | 0.82 | CTSK (0.54) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6184317 | 0.81 | CTSS (0.56) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001068645-A2 | N-CYANOMETHYLCARBOXAMIDES AND THEIR USE AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-09-20 | — | — | WO | claimed |