Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 6/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | FCER2 | P06734 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 4/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570081 | 0.93 | CTSL (0.43) | CTSLMMP1MMP2RENACE | |
| SCHEMBL7544678 | 0.91 | CTSL (0.39) | MEN1KMT2ACTSLMMP1MMP2 | |
| SCHEMBL7540704 | 0.91 | CTSL (0.39) | MEN1KMT2ACTSLMMP1FCER2 | |
| SCHEMBL7548201 | 0.91 | CTSL (0.42) | CTSLMMP1MMP2RENACE | |
| SCHEMBL7540085 | 0.91 | CTSL (0.42) | CTSLMMP1MMP2RENACE | |
| SCHEMBL7543417 | 0.90 | CTSL (0.41) | KMT2ACTSLMMP1MMP2REN | |
| SCHEMBL7541665 | 0.90 | MEN1 (0.46) | MEN1KMT2ACTSLMMP1FCER2 | |
| SCHEMBL7545704 | 0.89 | HDAC3 (0.46) | MEN1KMT2ACTSLMMP1REN | |
| SCHEMBL7569100 | 0.89 | CTSK (0.38) | MEN1KMT2ACTSLMMP1FCER2 | |
| SCHEMBL7541145 | 0.88 | CTSL (0.39) | MEN1KMT2ACTSLACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |