SCHEMBL754092

SCHEMBL754092

Cc1ccc(C(N)c2ccc(C)c(C)c2)cc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
LMNA P02545 2/20 0.39
TRPA1 O75762 1/20 0.38
PTGS1 P23219 1/20 0.38
CACNA1C Q13936 1/20 0.38
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
TP53 P04637 1/20 0.34
TDP1 Q9NUW8 4/20 0.33
TSHR P16473 2/20 0.33
S1PR1 P21453 1/20 0.33
S1PR3 Q99500 1/20 0.33
CASP1 P29466 1/20 0.33
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
ADRB2 P07550 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29582024 0.89 DPP4 (0.41) ALDH1A1LMNAMEN1KMT2A
SCHEMBL22867711 0.89 DPP4 (0.41) ALDH1A1LMNAMEN1KMT2A
SCHEMBL4604444 0.84 ALDH1A1 (0.46) ALDH1A1LMNATRPA1PTGS1CACNA1C
SCHEMBL13128971 0.82 ADRB2 (0.46) ALDH1A1LMNATRPA1PTGS1CACNA1C
SCHEMBL3650358 0.82 ADRB2 (0.46) ALDH1A1LMNATRPA1PTGS1CACNA1C
SCHEMBL13877347 0.82 ADRB2 (0.46) ALDH1A1LMNATRPA1PTGS1CACNA1C
Hydrochloric Acid SCHEMBL4223637 0.80 ADRB2 (0.44) ALDH1A1LMNATRPA1PTGS1CACNA1C
Hydrochloric Acid SCHEMBL7780522 0.80 ADRB2 (0.44) ALDH1A1LMNATRPA1PTGS1CACNA1C
SCHEMBL12086953 0.78 ALDH1A1 (0.41) ALDH1A1LMNATRPA1PTGS1CACNA1C
SCHEMBL21169655 0.78 ADRA2A (0.35) ALDH1A1LMNATRPA1CACNA1CTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0968239-B1 CONTINUOUS PROCESS FOR PREPARING A POLYURETHANE LATEX DOW GLOBAL TECHNOLOGIES INC (US) 2004-11-10 EP claimed
EP-1169368-B1 CONTINUOUS PROCESS FOR PREPARING A POLYURETHANE LATEX DOW GLOBAL TECHNOLOGIES INC (US) 2003-03-19 EP claimed
JP-2002537424-A 2002-11-05 JP claimed
EP-1169368-A1 CONTINUOUS PROCESS FOR PREPARING A POLYURETHANE LATEX THE DOW CHEMICAL COMPANY (US) 2002-01-09 EP claimed
WO-2000049062-A1 CONTINUOUS PROCESS FOR PREPARING A POLYURETHANE LATEX THE DOW CHEMICAL COMPANY (US) 2000-08-24 WO claimed
US-6087440-A Continuous process for preparing a polyurethane latex THE DOW CHEMICAL COMPANY (US) 2000-07-11 US claimed
EP-0968239-A1 CONTINUOUS PROCESS FOR PREPARING A POLYURETHANE LATEX THE DOW CHEMICAL COMPANY (US) 2000-01-05 EP claimed
US-5959027-A Continuous process for preparing a polyurethane latex THE DOW CHEMICAL COMPANY (US) 1999-09-28 US claimed
WO-1998041552-A1 CONTINUOUS PROCESS FOR PREPARING A POLYURETHANE LATEX THE DOW CHEMICAL COMPANY (US) 1998-09-24 WO claimed
US-20230303480-A1 Polybenzoxazole, Polyamide, Polyamide Solution, Insulating Material for High-Frequency Electronic Component, High-Frequency Electronic Component, High-Frequency Equipment, Insulating Material for Producing High-Frequency Electronic Component, Method for Producing Polyamide, Method for Producing Polybenzoxazole, Method for Producing Insulating Material for High-Frequency Electronic Component, and Diamine or Salt Thereof CENTRAL GLASS COMPANY, LIMITED (JP) 2023-09-28 US disclosed
US-20150247057-A1 POLYURETHANE DISPERSION BASED COATINGS HAVING ENHANCED REMOVABILITY DOW GLOBAL TECHNOLOGIES LLC (US) 2015-09-03 US disclosed
EP-2877510-A1 POLYURETHANE DISPERSION BASED COATINGS HAVING ENHANCED REMOVABILITY Dow Global Technologies LLC (US) 2015-06-03 EP disclosed
WO-2014047408-A1 POLYURETHANE DISPERSION BASED COATINGS HAVING ENHANCED REMOVABILITY DOW GLOBAL TECHNOLOGIES LLC (US) 2014-03-27 WO disclosed
EP-1901998-B1 PROCESS REACTOR WITH LAYERED PACKED BED HONEYWELL INT INC (US) 2012-03-21 EP disclosed
WO-1990011970-A1 PROCESS FOR REMOVAL OF ORGANIC POLLUTANTS FROM WASTE WATER ALLIED-SIGNAL INC. (US) 1990-10-18 WO disclosed
EP-0128642-B1 HERBICIDAL COMPOSITIONS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-08-31 EP disclosed
EP-0121851-B1 BIOLOGICALLY ACTIVE COMPOSITION FOR THE PURIFICATION OF WASTE WATER AND WASTE GASES BAYER AG (DE) 1988-01-13 EP disclosed
EP-0128642-A1 Herbicidal compositions IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-12-19 EP disclosed
EP-0121851-A2 Biologically active composition for the purification of waste water and waste gases BAYER AG (DE) 1984-10-17 EP disclosed
US-4379071-A Process for the production of microcapsules BAYER AKTIENGESELLSCHAFT (DE) 1983-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303480-A1 Polybenzoxazole, Polyamide, Polyamide Solution, Insulating Material for High-Frequency Electronic Component, High-Frequency Electronic Component, High-Frequency Equipment, Insulating Material for Producing High-Frequency Electronic Component, Method for Producing Polyamide, Method for Producing Polybenzoxazole, Method for Producing Insulating Material for High-Frequency Electronic Component, and Diamine or Salt Thereof PUF60, TET1, PBRM1 ALDH1A1 2031/4885LMNA 4375/4885TRPA1 2771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.