Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13877347 | 1.00 | ADRB2 (0.46) | ADRB2ALDH1A1LMNATRPA1PTGS1 | |
| SCHEMBL13128971 | 1.00 | ADRB2 (0.46) | ADRB2ALDH1A1LMNATRPA1PTGS1 | |
| Hydrochloric Acid SCHEMBL4223637 | 0.98 | ADRB2 (0.44) | ADRB2ALDH1A1LMNATRPA1PTGS1 | |
| Hydrochloric Acid SCHEMBL7780522 | 0.98 | ADRB2 (0.44) | ADRB2ALDH1A1LMNATRPA1PTGS1 | |
| SCHEMBL754092 | 0.82 | ALDH1A1 (0.46) | ADRB2ALDH1A1LMNATRPA1PTGS1 | |
| SCHEMBL4604444 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNATRPA1PTGS1CACNA1C | |
| SCHEMBL24495400 | 0.81 | LMNA (0.45) | ADRB2ALDH1A1LMNATRPA1PTGS1 | |
| SCHEMBL16392261 | 0.81 | ALDH1A1 (0.50) | ADRB2ALDH1A1LMNATRPA1PTGS1 | |
| SCHEMBL4368719 | 0.81 | ALDH1A1 (0.50) | ADRB2ALDH1A1LMNATRPA1PTGS1 | |
| SCHEMBL21817350 | 0.79 | ADRB2 (0.46) | ADRB2LMNAPTGS1PDE2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661538-A | Pyrazolo [3,4-d ] pyrimidine-4-ketone derivative and application thereof | 中国科学院精密测量科学与技术创新研究院 | 2025-03-21 | — | — | CN | disclosed |
| CN-111848494-A | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2020-10-30 | — | — | CN | disclosed |
| US-10799495-B2 | Aaptamine alkaloid derivatives and synthesis method and application thereof | RENJI HOSPITAL, SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE (CN) | 2020-10-13 | — | — | US | disclosed |
| CN-108299430-B | Benzodiazanaphthyridine alkaloid and synthesis method and application thereof | 上海交通大学医学院附属仁济医院 | 2020-09-18 | — | — | CN | disclosed |
| US-20190350926-A1 | AAPTAMINE ALKALOID DERIVATIVES AND SYNTHESIS METHOD AND APPLICATION THEREOF | RENJI HOSPITAL, SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE (CN) | 2019-11-21 | — | — | US | disclosed |
| EP-2962687-B1 | TAU AGGREGATION INHIBITOR | THE DOSHISHA (JP) | 2019-06-05 | — | — | EP | disclosed |
| US-9907799-B2 | Tau aggregation inhibitor | THE DOSHISHA (JP) | 2018-03-06 | — | — | US | disclosed |
| US-20160355458-A1 | INHIBITORS OF COGNITIVE DECLINE | COGNITION THERAPEUTICS, INC. | 2016-12-08 | — | — | US | disclosed |
| US-20160030437-A1 | TAU AGGREGATION INHIBITOR | NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY (JP) | 2016-02-04 | — | — | US | disclosed |
| EP-2962687-A1 | TAU AGGREGATION INHIBITOR | The Doshisha (JP) | 2016-01-06 | — | — | EP | disclosed |
| US-8084470-B2 | Substituted nicotinamide compounds and uses thereof | GRUENENTHAL GMBH (DE) | 2011-12-27 | — | — | US | disclosed |
| US-20100249101-A1 | MALONAMIDE DERIVATIVES WITH ANTITHROMBOTIC ACTIVITY | SANOFI-AVENTIS (FR) | 2010-09-30 | — | — | US | disclosed |
| EP-2188258-A1 | SUBSTITUTED NICOTINAMIDE COMPOUNDS AND THE USE THEREOF IN PHARMACEUTICAL PRODUCTS | Grünenthal GmbH (DE) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009036938-A1 | SUBSTITUTED NICOTINAMIDE COMPOUNDS AND THE USE THEREOF IN PHARMACEUTICAL PRODUCTS | Grünenthal GmbH (DE) | 2009-03-26 | — | — | WO | disclosed |
| US-20090076086-A1 | SUBSTITUTED NICOTINAMIDE COMPOUNDS AND USES THEREOF | GRUENENTHAL GMBH (DE) | 2009-03-19 | — | — | US | disclosed |
| CN-1626218-A | Cactus skin-health cream | WANG JINJIANG (CN) | 2005-06-15 | — | — | CN | disclosed |
| EP-0191496-B1 | TRIAZINE DERIVATIVES, A PROCESS FOR PREPARING THE DERIVATIVES, AND HERBICIDES CONTAINING THE DERIVATIVES AS THE EFFECTIVE COMPONENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4680054-A | Triazine derivatives, a process for preparing the derivatives, and herbicides containing the derivatives as the effective component | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1987-07-14 | — | — | US | disclosed |
| EP-0191496-A2 | Triazine Derivatives, a process for preparing the derivatives, and herbicides containing the derivatives as the effective component | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1986-08-20 | — | — | EP | disclosed |
| US-4191765-A | 1-Aryloxy-2-hydroxy-3-aminopropanes | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160030437-A1 | TAU AGGREGATION INHIBITOR | MAPT, PSEN2, PSEN1 | ADRB2 825/4885ALDH1A1 4120/4885LMNA 1864/4885 |
| US-20100249101-A1 | MALONAMIDE DERIVATIVES WITH ANTITHROMBOTIC ACTIVITY | F7, F9, TFPI | ADRB2 4456/4885ALDH1A1 293/4885LMNA 546/4885 |
| US-10799495-B2 | Aaptamine alkaloid derivatives and synthesis method and application thereof | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CHRM1, ATL3 | ADRB2 18/4885ALDH1A1 831/4885LMNA 1489/4885 |
| US-20160355458-A1 | INHIBITORS OF COGNITIVE DECLINE | PSEN2, ACHE, MAPT | ADRB2 508/4885ALDH1A1 3071/4885LMNA 3447/4885 |
| US-20090076086-A1 | SUBSTITUTED NICOTINAMIDE COMPOUNDS AND USES THEREOF | NNT, NAMPT, NADK | ADRB2 1205/4885ALDH1A1 281/4885LMNA 547/4885 |
| US-20190350926-A1 | AAPTAMINE ALKALOID DERIVATIVES AND SYNTHESIS METHOD AND APPLICATION THEREOF | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CHRM1, ATL3 | ADRB2 18/4885ALDH1A1 831/4885LMNA 1489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.