Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA4 | P22748 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA6 | P23280 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7551757 | 0.87 | HTR2A (0.43) | HTR2ACA2CA4POLBL3MBTL1 | |
| SCHEMBL7544301 | 0.77 | KDM4E (0.46) | HTR2AHTR2CHTR2BKDM4E | |
| SCHEMBL8670294 | 0.72 | KDM4E (0.40) | HTR2AHTR2CHTR2BKDM4E | |
| SCHEMBL7547973 | 0.69 | HTR2A (0.39) | HTR2ATSHRAPOBEC3AHTTAPOBEC3G | |
| SCHEMBL6782949 | 0.68 | TUBB4A (0.40) | POLBMAPTKMT2ATUBB4ATUBB | |
| SCHEMBL3914363 | 0.67 | KDM4E (0.47) | CA2CA4POLBTSHRMAPT | |
| SCHEMBL8411765 | 0.65 | HTR2A (0.46) | HTR2APOLBL3MBTL1HTR2CHTR2B | |
| SCHEMBL11188883 | 0.65 | HTR2A (0.43) | HTR2ACA2CA4POLBL3MBTL1 | |
| SCHEMBL7543660 | 0.65 | KDM4E (0.39) | L3MBTL1TSHRMAPTTUBB1KDM4E | |
| Nitrous Acid SCHEMBL7549271 | 0.65 | HTR2A (0.36) | HTR2ATSHRAPOBEC3AHTTAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883599-B1 | AMINOTETRALIN DERIVATIVES AND COMPOSITIONS AND METHOD OF USE THEREOF | ASTRAZENECA AB (SE) | 2002-06-05 | — | — | EP | disclosed |
| EP-0883599-A1 | AMINOTETRALIN DERIVATIVES AND COMPOSITIONS AND METHOD OF USE THEREOF | ZENECA LIMITED (GB) | 1998-12-16 | — | — | EP | disclosed |
| US-5807897-A | MUSCULAR DISORDERS | ZENECA LIMITED (GB) | 1998-09-15 | — | — | US | disclosed |
| WO-1997031887-A1 | AMINOTETRALIN DERIVATIVES AND COMPOSITIONS AND METHOD OF USE THEREOF | ZENECA LIMITED (GB) | 1997-09-04 | — | — | WO | disclosed |
| US-4374979-A | Regiospecific synthesis of anthracyclinone compounds such as daunomycinone | THE UNIVERSITY OF KANSAS ENDOWMENT ASSOCIATION (US) | 1983-02-22 | — | — | US | disclosed |
| EP-0063945-A1 | Process for the regiospecific synthesis of anthracyclinone compounds such as daunomycinone | THE UNIVERSITY OF KANSAS (US) | 1982-11-03 | — | — | EP | disclosed |