Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543660 | 0.86 | KDM4E (0.39) | KDM4EALDH1A1HPGDGAA | |
| SCHEMBL7544301 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL7548035 | 0.81 | ADORA3 (0.31) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL7548030 | 0.81 | ALDH1A1 (0.32) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL7547552 | 0.81 | ALDH1A1 (0.33) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL8908569 | 0.79 | ADRA1A (0.42) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL3319373 | 0.74 | DRD2 (0.40) | ACHE | |
| SCHEMBL30485650 | 0.74 | DRD2 (0.40) | ACHE | |
| SCHEMBL13497561 | 0.74 | PDE4B (0.36) | KDM4EALDH1A1TXNRD1 | |
| SCHEMBL8729417 | 0.73 | ACHE (0.45) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101885674-B | Preparation method of 5,8-dimethoxy-2-tetralin ketone | GANSU HAOTIAN CHEMEXPRESS CO LTD | 2015-03-11 | — | — | CN | claimed |
| CN-101885674-A | Preparation method of 5,8-dimethoxy-2-tetralin ketone | GANSU HAOTIAN CHEMEXPRESS CO LTD | 2010-11-17 | — | — | CN | claimed |
| CN-101885674-B | Preparation method of 5,8-dimethoxy-2-tetralin ketone | GANSU HAOTIAN CHEMEXPRESS CO LTD | 2015-03-11 | — | — | CN | disclosed |
| CN-101885674-B | Preparation method of 5,8-dimethoxy-2-tetralin ketone | GANSU HAOTIAN CHEMEXPRESS CO LTD | 2015-03-11 | — | — | CN | disclosed |
| CN-101885674-A | Preparation method of 5,8-dimethoxy-2-tetralin ketone | GANSU HAOTIAN CHEMEXPRESS CO LTD | 2010-11-17 | — | — | CN | disclosed |
| CN-101885674-A | Preparation method of 5,8-dimethoxy-2-tetralin ketone | GANSU HAOTIAN CHEMEXPRESS CO LTD | 2010-11-17 | — | — | CN | disclosed |
| EP-0883599-A1 | AMINOTETRALIN DERIVATIVES AND COMPOSITIONS AND METHOD OF USE THEREOF | ZENECA LIMITED (GB) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997031887-A1 | AMINOTETRALIN DERIVATIVES AND COMPOSITIONS AND METHOD OF USE THEREOF | ZENECA LIMITED (GB) | 1997-09-04 | — | — | WO | disclosed |