Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7774549 | 0.87 | RAB9A (0.42) | RAB9AALDH1A1NPC1SMN1; SMN2HPGD | |
| SCHEMBL7549342 | 0.87 | CA1 (0.42) | RAB9AALDH1A1MAPTKDM4ENPC1 | |
| SCHEMBL7541114 | 0.87 | SMN1; SMN2 (0.50) | RAB9ATDP1ALDH1A1MAPTNPC1 | |
| SCHEMBL15384064 | 0.87 | SMN1; SMN2 (0.50) | RAB9ATDP1ALDH1A1MAPTNPC1 | |
| SCHEMBL7540214 | 0.75 | SMN1; SMN2 (0.47) | RAB9AALDH1A1MAPTNPC1SMN1; SMN2 | |
| SCHEMBL7547525 | 0.72 | NPC1 (0.47) | RAB9ATDP1ALDH1A1MAPTKDM4E | |
| SCHEMBL7778947 | 0.69 | ALDH1A1 (0.48) | RAB9ATDP1ALDH1A1MAPTNPC1 | |
| SCHEMBL29023461 | 0.68 | MEN1 (0.35) | RAB9AMAPTNPC1SMN1; SMN2HPGD | |
| SCHEMBL4434068 | 0.67 | RAB9A (0.54) | RAB9AALDH1A1MAPTNPC1SMN1; SMN2 | |
| SCHEMBL4434071 | 0.67 | RAB9A (0.54) | RAB9AALDH1A1MAPTNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860432-B1 | 2-Phenyl-2-(2'-piperidinylidene) acetate derivative, process for manufacturing the same, and process for manufacturing optically active 2-phenyl-2(2'-piperidinyl) acetate derivative by asymmetrically hydrogenating the same | TAKASAGO PERFUMERY CO LTD (JP) | 2002-06-05 | — | — | EP | disclosed |
| EP-0949247-B1 | Process for the preparation of piperidinylidene derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-6008358-A | Process for the preparation of piperidinylidene derivative | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0949247-A1 | Process for the preparation of piperidinylidene derivatives | Takasago International Corporation (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5859249-A | CYCLIZATION A 7-(N-SUBSTITUTED AMINO)-3-OXO-2-PHENYLHEPTANOATE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0860432-A1 | 2-Phenyl-2-(2'-piperidinylidene) acetate derivative, process for manufacturing the same, and process for manufacturing optically active 2-phenyl-2(2'-piperidinyl) acetate derivative by asymmetrically hydrogenating the same | Takasago International Corporation (JP) | 1998-08-26 | — | — | EP | disclosed |