SCHEMBL7541641

SCHEMBL7541641

CO[Si](OC)(OC)OC=Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.45
NFE2L2 Q16236 2/20 0.41
MAOB P27338 1/20 0.41
TUBB1 Q9H4B7 2/20 0.40
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
TUBA3C P0DPH7 1/20 0.40
TUBA1B P68363 1/20 0.40
TUBA4A P68366 1/20 0.40
TUBB4B P68371 1/20 0.40
TUBB3 Q13509 1/20 0.40
TUBB2A Q13885 1/20 0.40
TUBB8 Q3ZCM7 1/20 0.40
TUBA3E Q6PEY2 1/20 0.40
TUBA1A Q71U36 1/20 0.40
TUBA1C Q9BQE3 1/20 0.40
TUBB6 Q9BUF5 1/20 0.40
TUBB2B Q9BVA1 1/20 0.40
CYP1A1 P04798 1/20 0.40
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL456141 0.82 TRPA1 (0.44) TRPA1NFE2L2MAOBTUBB1TUBB4A
SCHEMBL770392 0.78 MAOB (0.44) TRPA1NFE2L2MAOBMEN1KMT2A
SCHEMBL10682846 0.78 MAOB (0.44) TRPA1NFE2L2MAOBMEN1KMT2A
SCHEMBL28090503 0.76 RELA (0.43) TRPA1NFE2L2MAOBTUBB1TUBB4A
SCHEMBL14681134 0.75 TRPA1 (0.54) TRPA1NFE2L2MAOBTUBB1TUBB4A
SCHEMBL1399923 0.75 TRPA1 (0.54) TRPA1NFE2L2MAOBTUBB1TUBB4A
SCHEMBL14910 0.75 TRPA1 (0.54) TRPA1NFE2L2MAOBTUBB1TUBB4A
SCHEMBL27748919 0.74 MAOB (0.44) TRPA1NFE2L2MAOBCYP1A2MEN1
SCHEMBL5888604 0.73 RELA (0.44) TRPA1MAOBCYP1A1CYP1A2CYP1B1
SCHEMBL14843542 0.73 HTR2A (0.40) TRPA1MAOBMEN1KMT2AALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0805186-B1 THERMOSETTING COMPOSITION, METHOD OF FINISH COATING, AND COATED ARTICLES NOF CORP (JP) 2002-05-29 EP disclosed