Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.48 |
| ▸ | ACE | P12821 | 8/20 | 0.48 |
| ▸ | CPA1 | P15085 | 7/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 7/20 | 0.48 |
| ▸ | MMP3 | P08254 | 4/20 | 0.46 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538620 | 0.94 | FOLH1 (0.45) | MMEACECPA1ACE2MMP3 | |
| SCHEMBL7538668 | 0.94 | MME (0.43) | MMEACECPA1ACE2MMP3 | |
| SCHEMBL7547253 | 0.93 | MME (0.42) | MMEACECPA1ACE2MMP3 | |
| SCHEMBL7542336 | 0.92 | MMP1 (0.45) | MMEACECPA1ACE2MMP3 | |
| SCHEMBL7543615 | 0.90 | ACE (0.40) | MMEACECPA1ACE2MMP3 | |
| SCHEMBL7538785 | 0.87 | FOLH1 (0.54) | MMEACECPA1ACE2MMP3 | |
| SCHEMBL7541870 | 0.87 | FOLH1 (0.54) | MMEACECPA1ACE2MMP3 | |
| SCHEMBL7539261 | 0.86 | MMP3 (0.47) | MMEACECPA1ACE2MMP3 | |
| SCHEMBL7540008 | 0.86 | MMP3 (0.50) | MMEACECPA1ACE2MMP3 | |
| SCHEMBL7547257 | 0.81 | FOLH1 (0.55) | MMEACECPA1ACE2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |