Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 8/20 | 0.47 |
| ▸ | MME | P08473 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 6/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7542688 | 0.94 | FOLH1 (0.46) | MMP3MMEACECPA1ACE2 | |
| SCHEMBL7540859 | 0.94 | KMT2A (0.44) | MMP3MMEACECPA1ACE2 | |
| SCHEMBL7538809 | 0.93 | MMP1 (0.47) | MMP3MMP2CTSLCTSSMMP1 | |
| SCHEMBL7540570 | 0.88 | ITGB1 (0.54) | MMP3MMEACECPA1ACE2 | |
| SCHEMBL7546168 | 0.88 | ITGB1 (0.54) | MMP3MMEACECPA1ACE2 | |
| SCHEMBL7541912 | 0.86 | MME (0.48) | MMP3MMEACECPA1ACE2 | |
| SCHEMBL7538353 | 0.86 | MMP3 (0.51) | MMP3MMEACECPA1ACE2 | |
| SCHEMBL7570081 | 0.85 | CTSL (0.43) | MMP3MMEACECPA1ACE2 | |
| SCHEMBL7547048 | 0.82 | CTSL (0.44) | MMP3MMEACECPA1ACE2 | |
| SCHEMBL7540003 | 0.82 | CTSL (0.44) | MMP3MMP2CTSLITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |