Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | MMP2 | P08253 | 5/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | FCER2 | P06734 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543803 | 0.93 | CTSK (0.43) | CTSKCTSSMMP2MMP1CTSL | |
| SCHEMBL7539988 | 0.90 | PDF (0.38) | CTSKCTSSMMP1FCER2CTSL | |
| SCHEMBL7569173 | 0.90 | CTSK (0.41) | CTSKCTSSMMP2MMP1CTSL | |
| SCHEMBL7571304 | 0.90 | CTSK (0.41) | CTSKCTSSMMP2CTSLREN | |
| SCHEMBL7547089 | 0.90 | CTSS (0.35) | CTSKCTSSMMP1FCER2CTSL | |
| SCHEMBL7571661 | 0.90 | CTSK (0.40) | CTSKCTSSMMP2MMP1CTSL | |
| SCHEMBL7546030 | 0.89 | MEN1 (0.42) | MMP2MMP1FCER2MMP14FPR2 | |
| SCHEMBL7541963 | 0.89 | MEN1 (0.42) | CTSKCTSSMMP2MMP1FCER2 | |
| SCHEMBL7570635 | 0.88 | MMP1 (0.41) | CTSKCTSSMMP1CTSLFPR2 | |
| SCHEMBL7567387 | 0.87 | CTSS (0.34) | CTSKCTSSMMP1FCER2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |