Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 15/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 15/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.46 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4124237 | 0.78 | HPGD (0.42) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL9643202 | 0.77 | PTGS1 (0.51) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL11468007 | 0.76 | APP (0.64) | PTGS1PTGS2OPRK1HTTKMT2A | |
| Loxoprofen SCHEMBL11133884 | 0.75 | PTGS1 (1.00) | PTGS1PTGS2OPRK1HTTKMT2A | |
| Loxoprofen SCHEMBL28914092 | 0.75 | PTGS1 (1.00) | PTGS1PTGS2OPRK1HTTKMT2A | |
| Loxoprofen SCHEMBL24423 | 0.75 | PTGS1 (1.00) | PTGS1PTGS2OPRK1HTTKMT2A | |
| Loxoprofen SCHEMBL28562193 | 0.75 | PTGS1 (1.00) | PTGS1PTGS2OPRK1HTTKMT2A | |
| Loxoprofen SCHEMBL28562194 | 0.75 | PTGS1 (1.00) | PTGS1PTGS2OPRK1HTTKMT2A | |
| Loxoprofen SCHEMBL28914090 | 0.75 | PTGS1 (1.00) | PTGS1PTGS2OPRK1HTTKMT2A | |
| Loxoprofen SCHEMBL14312087 | 0.75 | PTGS1 (1.00) | PTGS1PTGS2OPRK1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1625411-A | Combination of a NSAID and a PDE-4 inhibitor | ALTANA PHARMA AG (DE) | 2005-06-08 | — | — | CN | claimed |
| CN-119241545-A | Matrine tricyclic derivative and application thereof in preparation of medicines for treating hepatic fibrosis | 中国人民解放军海军军医大学 | 2025-01-03 | — | — | CN | disclosed |
| US-20210078941-A1 | Method For Preparing Substituted Phenylacetic Acid Derivative | JIANGSU RUIKE MEDICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2021-03-18 | — | — | US | disclosed |
| EP-3680227-A1 | METHOD FOR PREPARING SUBSTITUTED PHENYLACETIC ACID DERIVATIVE | Jiangsu Ruike Medical Science And Technology Co., Ltd. (CN) | 2020-07-15 | — | — | EP | disclosed |
| CN-1278672-C | Pharmaceutical composition for intramuscular injection containing loxoprofen | SHIN POONG PHARMACEUTICAL CO (KR) | 2006-10-11 | — | — | CN | disclosed |
| CN-1400892-A | Pharmaceutical composition for intramuscular injection containing loxoprofen | SHIN POONG PHARMACEUTICAL CO (KR) | 2003-03-05 | — | — | CN | disclosed |
| WO-2002047661-A1 | PHARMACEUTICAL COMPOSITION FOR INTRAMUSCULAR INJECTION CONTAINING LOXOPROFEN | SHIN POONG PHARMACEUTICAL CO., LTD. (KR) | 2002-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210078941-A1 | Method For Preparing Substituted Phenylacetic Acid Derivative | ALOX5, LOXL4, CYP3A5 | PTGS1 654/4885PTGS2 731/4885OPRK1 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.