SCHEMBL20528820

SCHEMBL20528820

CC1=C(C)C([Si](C)(C)C2C=C(c3ccccc3)c3ccccc32)C(C)=C1C

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15815479 0.87
SCHEMBL7542406 0.79 ALDH1A1 (0.33) NPC1ALDH1A1HPGDTSHRRAB9A
SCHEMBL20996218 0.75 MEN1 (0.33)
SCHEMBL30084512 0.75 MEN1 (0.33)
SCHEMBL23141288 0.73
SCHEMBL20656716 0.73
SCHEMBL29897864 0.73
SCHEMBL21035817 0.72 BCHE (0.33)
SCHEMBL31185423 0.70
SCHEMBL28219801 0.70 AURKA (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3606931-B1 DIHYDROCARBYL-SILYL-BRIDGED-SUBSTITUTED CYCLOPENTADIENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION SABIC GLOBAL TECHNOLOGIES BV (NL) 2025-08-27 EP disclosed
EP-3418311-B1 HYBRID SUPPORTED CATALYST LG CHEMICAL LTD (KR) 2023-03-08 EP disclosed
US-11352386-B2 Dihydrocarbyl-silyl-bridged-substituted cyclopentadienyl metallocene complexes for olefin polymerization SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-06-07 US disclosed
US-11091571-B2 Hybrid supported catalyst LG CHEM, LTD. 2021-08-17 US disclosed
US-20200199165-A1 DIHYDROCARBYL-SILYL-BRIDGED-SUBSTITUTED CYCLOPENTADIENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-06-25 US disclosed
US-20200123290-A1 HYBRID SUPPORTED CATALYST LG CHEM, LTD. (KR) 2020-04-23 US disclosed
EP-3606931-A1 DIHYDROCARBYL-SILYL-BRIDGED-SUBSTITUTED CYCLOPENTADIENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION SABIC Global Technologies B.V. (NL) 2020-02-12 EP disclosed
EP-3418311-A1 HYBRID SUPPORT CATALYST LG Chem, Ltd. (KR) 2018-12-26 EP disclosed
WO-2018185176-A1 DIHYDROCARBYL-SILYL-BRIDGED-SUBSTITUTED CYCLOPENTADIENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-10-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200123290-A1 HYBRID SUPPORTED CATALYST BECN1, PUF60, POLN NPC1 1742/4885ALDH1A1 4554/4885HPGD 3158/4885
US-11352386-B2 Dihydrocarbyl-silyl-bridged-substituted cyclopentadienyl metallocene complexes for olefin polymerization C9, APOL1, ACSL3 NPC1 2676/4885ALDH1A1 832/4885HPGD 2505/4885
US-11091571-B2 Hybrid supported catalyst BECN1, PUF60, POLN NPC1 1742/4885ALDH1A1 4554/4885HPGD 3158/4885
US-20200199165-A1 DIHYDROCARBYL-SILYL-BRIDGED-SUBSTITUTED CYCLOPENTADIENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION APOL1, ACSL3, OXA1L NPC1 2659/4885ALDH1A1 939/4885HPGD 2688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.