Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 3/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719784 | 0.80 | SYK (0.58) | SYKPARP10KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1936855 | 0.80 | LTA4H (0.59) | MGMTALDH1A1SMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL27163847 | 0.79 | LTA4H (0.57) | MGMTSMN1; SMN2L3MBTL1 | |
| SCHEMBL30418203 | 0.79 | KDM4E (0.45) | MGMTSYKPARP10GABRA1GABRG2 | |
| SCHEMBL28696981 | 0.77 | KMT2A (0.39) | KDM4EALDH1A1 | |
| SCHEMBL9117255 | 0.75 | LTA4H (0.67) | MGMTSYKPARP10KDM4EALDH1A1 | |
| SCHEMBL1647418 | 0.73 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL29977462 | 0.73 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL31700841 | 0.73 | NOS3 (0.34) | KDM4EALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL30361386 | 0.73 | PARP10 (0.64) | SYKPARP10KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020035134-A1 | Indoline derivatives useful as 5-HT-2C receptor antagonists | SMITHKLINE BEECHAM P.L.C. | 2002-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035134-A1 | Indoline derivatives useful as 5-HT-2C receptor antagonists | HTR2C, HTR1A, HTR1D | MGMT 1854/4885SYK 1978/4885PARP10 3054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.