Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ATIC | P31939 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14176707 | 0.86 | ALDH1A1 (0.49) | SIRT1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8528173 | 0.84 | SIRT1 (0.49) | SIRT1NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL11346051 | 0.84 | SIRT1 (0.45) | SIRT1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11674905 | 0.82 | SIRT1 (0.46) | SIRT1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7535327 | 0.81 | NR4A1 (0.59) | SIRT1NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL11835677 | 0.80 | KDM4E (0.54) | NR4A1NR4A2NR4A3ALDH1A1MEN1 | |
| SCHEMBL7540795 | 0.80 | PKM (0.52) | NR4A1NR4A2NR4A3ALDH1A1MEN1 | |
| SCHEMBL30838413 | 0.79 | NR4A1 (0.65) | NR4A1NR4A2NR4A3ALDH1A1MAPT | |
| SCHEMBL30838412 | 0.79 | NR4A1 (0.65) | NR4A1NR4A2NR4A3ALDH1A1MAPT | |
| SCHEMBL28798 | 0.79 | NR4A1 (0.65) | NR4A1NR4A2NR4A3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020094993-A1 | Compositions for repelling crawling insects | S.C. JOHNSON & SON, INC. | 2002-07-18 | — | — | US | disclosed |
| US-4007180-A | POLYESTERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094993-A1 | Compositions for repelling crawling insects | ACHE, DDT, GAP43 | SIRT1 4205/4885NR4A1 4435/4885NR4A2 3917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.