SCHEMBL754313

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL756570	0.79	NR3C2 (0.48)	PTGDR2WNT3ANR3C2NPC1TP53
	SCHEMBL4386993	0.73	SIGMAR1 (0.46)	SIGMAR1ALDH1A1CYP19A1SMN1; SMN2
	SCHEMBL14547167	0.73	SIGMAR1 (0.46)	SIGMAR1ALDH1A1CYP19A1SMN1; SMN2
	SCHEMBL3890809	0.72	RAB9A (0.50)	PTGDR2ALDH1A1WNT3ANR3C2NPC1
	SCHEMBL6189452	0.71	SIGMAR1 (0.45)	SIGMAR1ALDH1A1CYP19A1
	SCHEMBL22310964	0.71	PTGDR2 (0.38)	PTGDR2WNT3ASMN1; SMN2MAPK1
	SCHEMBL20622236	0.70	SIGMAR1 (0.44)	SIGMAR1ALDH1A1CYP19A1
	SCHEMBL26008288	0.69	HSD17B10 (0.55)	—
	SCHEMBL31073989	0.69	HSD17B10 (0.55)	—
	SCHEMBL7647810	0.69	SIGMAR1 (0.44)	SIGMAR1ALDH1A1CYP19A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.