Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7553256 | 0.87 | RAB9A (0.40) | KMT2ARAB9ANPC1SMN1; SMN2PKM | |
| SCHEMBL7551656 | 0.82 | TDP1 (0.39) | KMT2ARAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7546700 | 0.79 | ALOX5 (0.39) | KMT2ARAB9ANPC1SMN1; SMN2PKM | |
| SCHEMBL7553608 | 0.78 | NAPRT (0.46) | KMT2ANAPRTALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL7548361 | 0.77 | NAPRT (0.53) | KMT2ARAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8798744 | 0.77 | NAPRT (0.44) | KMT2ARAB9AL3MBTL1NAPRTALDH1A1 | |
| SCHEMBL7556390 | 0.76 | NAPRT (0.37) | KMT2ARAB9ANPC1L3MBTL1NAPRT | |
| SCHEMBL8813141 | 0.76 | NAPRT (0.44) | KMT2ARAB9ANPC1NAPRTALDH1A1 | |
| SCHEMBL19857454 | 0.76 | NAPRT (0.57) | KMT2ARAB9ASMN1; SMN2L3MBTL1NAPRT | |
| SCHEMBL28474528 | 0.76 | MAPK1 (0.55) | KMT2ARAB9ANPC1SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049708-A9 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | — | 1998-05-22 | — | — | WO | disclosed |