Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548395 | 0.89 | ALOX5 (0.38) | ALOX5L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7546681 | 0.82 | TDP1 (0.37) | NAPRTL3MBTL1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL7547894 | 0.81 | MAPT (0.46) | NAPRTKMT2AKDM4EMEN1 | |
| SCHEMBL7543322 | 0.79 | KMT2A (0.41) | NAPRTL3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL9059311 | 0.79 | NAPRT (0.34) | NAPRTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7551790 | 0.77 | SGMS2 (0.36) | NAPRTKDM4ETP53POLBMAPK1 | |
| SCHEMBL8805065 | 0.75 | SHBG (0.44) | NAPRTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8799100 | 0.73 | KDM4E (0.44) | ALOX5NAPRTKMT2ANPC1RAB9A | |
| SCHEMBL7551656 | 0.72 | TDP1 (0.39) | NAPRTL3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL19857454 | 0.72 | NAPRT (0.57) | NAPRTL3MBTL1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049708-A9 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | — | 1998-05-22 | — | — | WO | disclosed |