Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.39 |
| ▸ | PYGL | P06737 | 2/20 | 0.39 |
| ▸ | PYGM | P11217 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11118093 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MAPTL3MBTL1KDM4ETSHR | |
| SCHEMBL31758112 | 0.80 | FFAR1 (0.41) | ALDH1A1DPP4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29958724 | 0.78 | PYGL (0.40) | DPP4RIPK1PYGLPYGMMTNR1A | |
| SCHEMBL7564705 | 0.78 | IDO1 (0.46) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL2216388 | 0.75 | NPC1 (0.47) | ALDH1A1MAPTKDM4EBRD4RIPK1 | |
| SCHEMBL11116054 | 0.72 | MAPT (0.43) | ALDH1A1MAPTL3MBTL1KDM4ETSHR | |
| SCHEMBL4342519 | 0.72 | IDO1 (0.41) | ALDH1A1MAPTDPP4RIPK1PYGL | |
| SCHEMBL4655446 | 0.72 | ACE (0.62) | KDM4ERIPK1 | |
| SCHEMBL7756853 | 0.72 | ACE (0.62) | KDM4ERIPK1 | |
| SCHEMBL7760802 | 0.72 | ACE (0.62) | KDM4ERIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119954-A2 | 3-Amino-1-benzazepin-2-one-1-alcanoic acids, process for their preparation, their pharmaceutical preparation as well as their therapeutic use | CIBA-GEIGY AG (CH) | 1984-09-26 | — | — | EP | disclosed |
| EP-0119955-A2 | 3-(5-Aminopentyl)-amino-1-benzazepin-2-one-1-alcanoic acids, process for their preparation, their pharmaceutical preparation as well as their therapeutic use | CIBA-GEIGY AG (CH) | 1984-09-26 | — | — | EP | disclosed |
| EP-0072352-A1 | Benzazepin-2-ones, process for their preparation, pharmaceutical preparations containing these compounds and the compounds for therapeutical use | CIBA-GEIGY AG (CH) | 1983-02-16 | — | — | EP | disclosed |