SCHEMBL7543787

SCHEMBL7543787

CS(=O)(=O)OCc1nc2ccc(F)cc2s1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFER P55789 2/20 0.45
AXL P30530 1/20 0.45
SMN1; SMN2 Q16637 5/20 0.44
KMT2A Q03164 4/20 0.44
NPC1 O15118 4/20 0.44
RAB9A P51151 4/20 0.44
PDPK1 O15530 1/20 0.44
DYRK1A Q13627 1/20 0.44
PTPN1 P18031 1/20 0.43
MAPT P10636 4/20 0.42
KDM4E B2RXH2 3/20 0.42
MEN1 O00255 3/20 0.42
LMNA P02545 3/20 0.42
ALDH1A1 P00352 3/20 0.42
PKM P14618 1/20 0.42
ALOX12 P18054 1/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
HPGD P15428 3/20 0.41
GAA P10253 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1787762 0.80 CYP1A2 (0.60) SMN1; SMN2KMT2ANPC1RAB9AMAPT
SCHEMBL6630285 0.76 NPC1 (0.63) GFERAXLSMN1; SMN2KMT2ANPC1
SCHEMBL9259300 0.73 GFER (0.53) GFERAXLSMN1; SMN2KMT2ANPC1
SCHEMBL1729400 0.72 GFER (0.61) GFERAXLSMN1; SMN2KMT2ANPC1
SCHEMBL7222770 0.72 GFER (0.56) GFERAXLSMN1; SMN2KMT2ANPC1
SCHEMBL7547176 0.72 GFER (0.56) GFERAXLSMN1; SMN2KMT2ANPC1
SCHEMBL8465212 0.72 GFER (0.56) GFERAXLSMN1; SMN2KMT2ANPC1
SCHEMBL21684632 0.72 PTGER1 (0.37)
SCHEMBL21685185 0.72 DHFR (0.41)
SCHEMBL27338393 0.72 GFER (0.51) GFERAXLSMN1; SMN2KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0795550-B1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO CO (JP) 2002-06-05 EP disclosed
US-5736487-A HERBICIDES SANKYO COMPANY, LIMITED (JP) 1998-04-07 US disclosed
EP-0795550-A1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO COMPANY LIMITED (JP) 1997-09-17 EP disclosed