Hydrochloric Acid

Hydrochloric Acid

SCHEMBL7544025

[Cl-].[Cl-].[V+2]C1c2ccccc2-c2ccccc21

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 3/20 0.35
CHRM2 known ✓ P08172 1/20 0.35
CHRM1 known ✓ P11229 1/20 0.35
SLC6A2 known ✓ P23975 1/20 0.35
SLC6A3 known ✓ Q01959 1/20 0.35
GPR3 P46089 2/20 0.44
HTR2A P28223 2/20 0.44
CYP19A1 P11511 1/20 0.39
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
NCOR2 Q9Y618 1/20 0.38
POLB P06746 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
BCHE P06276 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3385863 0.73 GPR3 (0.46) GPR3HTR2ACYP19A1HDAC3HDAC4
SCHEMBL6936104 0.73 GPR3 (0.46) GPR3HTR2ACYP19A1HDAC3HDAC4
SCHEMBL524603 0.71 GPR3 (0.50) GPR3HTR2ACYP19A1HDAC3HDAC4
SCHEMBL29950614 0.71 GPR3 (0.50) GPR3HTR2ACYP19A1HDAC3HDAC4
Hydrochloric Acid SCHEMBL1985361 0.71 GPR3 (0.44) GPR3HTR2ACYP19A1HDAC3HDAC4
Hydrochloric Acid SCHEMBL6812758 0.71 GPR3 (0.44) GPR3HTR2ACYP19A1HDAC3HDAC4
Hydrochloric Acid SCHEMBL540140 0.71 GPR3 (0.44) GPR3HTR2ACYP19A1HDAC3HDAC4
SCHEMBL6814556 0.71 HTR2A (0.50) GPR3HTR2ACYP19A1HDAC3HDAC4
Hydrochloric Acid SCHEMBL7944465 0.71 GPR3 (0.44) GPR3HTR2ACYP19A1HDAC3HDAC4
Hydrochloric Acid SCHEMBL3381707 0.71 GPR3 (0.44) GPR3HTR2ACYP19A1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0841375-B1 Impact-resistant polystyrene resin composition UBE INDUSTRIES (JP) 2002-05-22 EP disclosed
EP-0778291-B1 Catalyst and process for producing conjugated diene polymer UBE INDUSTRIES (JP) 2001-03-28 EP disclosed
US-6071845-A OBTAINED BY CONTACTING A COMPOUND OF A TRANSITION METAL OF THE GROUP V OF THE PERIODIC TABLE WITH AN IONIC COMPOUND COMPRISING A NON-COORDINATING ANION AND A CATION AND AN ALUMINOXANE UBE INDUSTRIES, LTD. (JP) 2000-06-06 US disclosed
US-5981667-A CONTAINING DISPERSED PARTICLES OF HIGH-CIS HIGH-VINYL POLYBUTADIENE COMPRISING FROM 65 TO 95% CIS-1,4-STRUCTURES AND FROM 30 TO 4% 1,2-STRUCTURES UBE INDUSTRIES, LTD. (JP) 1999-11-09 US disclosed
EP-0841375-A1 Impact-resistant polystyrene resin composition UBE INDUSTRIES, LTD. (JP) 1998-05-13 EP disclosed
EP-0778291-A1 Catalyst and process for producing conjugated diene polymer UBE INDUSTRIES, LTD. (JP) 1997-06-11 EP disclosed