SCHEMBL8523950

SCHEMBL8523950

C=CCN1CNc2cc(F)ccc21

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRIA2 P42262 3/20 0.37
GRIA1 P42261 2/20 0.37
GRIA3 P42263 2/20 0.37
GRIA4 P48058 2/20 0.37
HDAC1 Q13547 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.33
MAPT P10636 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SLC6A2 P23975 2/20 0.31
DRD3 P35462 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
CHRM1 P11229 1/20 0.31
SLC6A4 P31645 1/20 0.31
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8469492 0.81 GRIA2 (0.43) GRIA2GRIA1GRIA3GRIA4HDAC1
SCHEMBL8523571 0.80 KMT2A (0.43) GRIA2GRIA1GRIA3GRIA4HDAC1
SCHEMBL8524767 0.77 HRH3 (0.40) GRIA2GRIA1GRIA3GRIA4TDP1
SCHEMBL8523029 0.77 DRD2 (0.37) GRIA2GRIA1GRIA3GRIA4HDAC1
SCHEMBL7544166 0.76 GAA (0.42) GRIA2GRIA1GRIA3GRIA4MAPT
SCHEMBL8469923 0.73 GRIA1 (0.44) GRIA2GRIA1GRIA3GRIA4ALDH1A1
SCHEMBL21991684 0.71 MAPT (0.33) PTGDR2MAPTTDP1GAALMNA
SCHEMBL20888864 0.69 PTGDR2 (0.32) PTGDR2MAPTTDP1
SCHEMBL29556963 0.68 NOTUM (0.39) GRIA2GRIA1GRIA3GRIA4HDAC1
SCHEMBL8756210 0.67 KMT2A (0.43) GRIA2GRIA1GRIA3GRIA4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5968725-A MATERIAL COMPRISING ON SUPPORT SILVER HALIDE PHOTOSENSITIVE LAYER CONTAINING ORGANIC SILVER SALT, REDUCING AGENT, ULTRAHIGH CONTRAST PROMOTING AGENT, SELECTED HETEROCYCLIC MERCAPTO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1999-10-19 US disclosed
US-5236807-A Negative, hydrazine compound FUJI PHOTO FILM CO., LTD. (JP) 1993-08-17 US disclosed
US-4769316-A Method for restraining the formation of re-reversal negative image in direct positive silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1988-09-06 US disclosed