Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184989 | 0.90 | BDKRB1 (0.50) | BDKRB1FAAHTRPV1CYP3A4CYP2C9 | |
| SCHEMBL185605 | 0.89 | FAAH (0.46) | BDKRB1FAAHTRPV1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13128626 | 0.89 | BDKRB1 (0.61) | BDKRB1SMN1; SMN2ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL185085 | 0.88 | BDKRB1 (0.47) | BDKRB1FAAHTRPV1SMN1; SMN2ALDH1A1 | |
| SCHEMBL185374 | 0.82 | MEN1 (0.47) | BDKRB1FAAHTRPV1MEN1KMT2A | |
| SCHEMBL754425 | 0.82 | PPARD (0.44) | BDKRB1FAAHTRPV1SMN1; SMN2ALDH1A1 | |
| SCHEMBL185745 | 0.81 | BDKRB1 (0.43) | BDKRB1FAAHTRPV1CYP3A4CYP2C9 | |
| SCHEMBL185958 | 0.80 | BDKRB1 (0.44) | BDKRB1FAAHTRPV1MEN1KMT2A | |
| SCHEMBL765812 | 0.80 | BDKRB1 (0.63) | BDKRB1SMN1; SMN2ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL756449 | 0.80 | BDKRB1 (0.46) | BDKRB1FAAHSMN1; SMN2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |