SCHEMBL754438

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16925510	0.77	ALDH1A1 (0.52)	ALDH1A1POLBRAB9ALMNAKDM4E
	SCHEMBL3557026	0.72	PTGER4 (0.39)	TACR3LMNAKDM4EMEN1KMT2A
	SCHEMBL752046	0.70	POLB (0.53)	ALDH1A1TACR3POLBKDM4E
	SCHEMBL753481	0.69	POLB (0.51)	ALDH1A1POLBLMNAKDM4EMEN1
	SCHEMBL825960	0.66	PTGS1 (0.38)	ALDH1A1POLBRAB9ALMNAKDM4E
	SCHEMBL17921816	0.66	POLB (0.50)	ALDH1A1TACR3POLBKDM4E
	SCHEMBL1332816	0.64	POLB (0.50)	ALDH1A1TACR3POLBRAB9ALMNA
	SCHEMBL3087952	0.63	APP (0.48)	NUDT1KMT2A
	SCHEMBL9061013	0.63	CES2 (0.48)	ALDH1A1RAB9AMEN1KMT2A
	SCHEMBL6625005	0.63	TDP1 (0.59)	ALDH1A1POLBLMNAKDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.