Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PTPRC | P08575 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22353300 | 0.89 | GAA (0.71) | TSHRPOLBGAAGLAPDK2 | |
| SCHEMBL6447369 | 0.77 | TSHR (0.40) | TSHRPOLBGAAGLAPDK2 | |
| SCHEMBL22722975 | 0.76 | TSHR (0.43) | TSHRPOLBGAAGLAPDK2 | |
| SCHEMBL15547709 | 0.76 | ADRA2B (0.46) | TSHRPOLBGAAGLAMAPK1 | |
| SCHEMBL9904799 | 0.74 | TSHR (0.43) | TSHRPOLBGAAGLAMAPK1 | |
| SCHEMBL30140345 | 0.74 | CYP3A4 (0.48) | TSHRPOLBGAAGLAMAPK1 | |
| SCHEMBL15966711 | 0.72 | KDM4E (0.39) | TSHRPOLBGAAGLAPDK2 | |
| SCHEMBL17987614 | 0.72 | GAA (0.71) | TSHRPOLBGAAGLAPDK2 | |
| SCHEMBL345797 | 0.71 | PRKCI (0.45) | TSHRPOLBGAAGLAMAPK1 | |
| SCHEMBL10486849 | 0.69 | ALDH1A1 (0.34) | TSHRPOLBGAAGLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725284-B1 | Ocular lens material | MENICON CO LTD (JP) | 2002-05-22 | — | — | EP | disclosed |
| EP-0634673-B1 | Ocular lens material | MENICON CO LTD (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5703143-A | SILICON-CONTAINING POLYPHENYLENE ETHER POLYMER | MENICON CO., LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| US-5605942-A | POLYIMIDE HAVING EXCELLENT TRANSPARENCY, OXYGEN PERMEABILITY, HEAT RESISTANCE, ULTRAVIOLET LIGHT ABSORPTION | MENICON CO., LTD. (JP) | 1997-02-25 | — | — | US | disclosed |
| EP-0725284-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1996-08-07 | — | — | EP | disclosed |
| US-5543442-A | POLYIMIDESILOXANE COPOLYMER | MENICON CO., LTD. (JP) | 1996-08-06 | — | — | US | disclosed |
| EP-0634673-A1 | Ocular lens material | Menicon Co., Ltd. (JP) | 1995-01-18 | — | — | EP | disclosed |