Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1RN | P18510 | 5/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541803 | 1.00 | IL1RN (0.49) | IL1RNERAP2ERAP1TSHRPPARG | |
| SCHEMBL7539136 | 0.91 | GPR34 (0.50) | PPARGPSMB5ALDH1A1 | |
| SCHEMBL7539133 | 0.91 | GPR34 (0.50) | PPARGPSMB5ALDH1A1 | |
| SCHEMBL7544851 | 0.81 | IL1RN (0.53) | IL1RNERAP2ERAP1TSHRPPARG | |
| SCHEMBL7544847 | 0.81 | IL1RN (0.53) | IL1RNERAP2ERAP1TSHRPPARG | |
| SCHEMBL7538677 | 0.72 | ACE (0.55) | PPARGPSMB5 | |
| SCHEMBL7538685 | 0.72 | ACE (0.55) | PPARGPSMB5 | |
| SCHEMBL7538682 | 0.72 | ALDH1A1 (0.46) | IL1RNERAP2ERAP1TSHRPPARG | |
| SCHEMBL7538679 | 0.72 | ALDH1A1 (0.46) | IL1RNERAP2ERAP1TSHRPPARG | |
| SCHEMBL14855487 | 0.71 | MAOB (0.49) | PPARGCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |