SCHEMBL754497

SCHEMBL754497

CC(C)(C)OCC(COC(C)(C)C)(COC(C)(C)C)COC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.36
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19543667 0.90 MAPK1 (0.32) MAPK1
SCHEMBL17708256 0.90 MAPK1 (0.32) MAPK1
SCHEMBL23964464 0.87 ALDH1A1 (0.32) MAPK1ALDH1A1
SCHEMBL12555908 0.83 TSHR (0.33) MAPK1ALDH1A1TSHRTDP1
SCHEMBL19542925 0.83 TSHR (0.33) MAPK1ALDH1A1TSHRTDP1
SCHEMBL13538680 0.83 TSHR (0.33) MAPK1ALDH1A1TSHRTDP1
SCHEMBL23958969 0.83
SCHEMBL14213292 0.81 MAPK1 (0.36) MAPK1ALDH1A1TSHR
SCHEMBL19655069 0.81 ALDH1A1 (0.33) MAPK1ALDH1A1
SCHEMBL16883925 0.81 MAPK1 (0.36) MAPK1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4298182-B1 DIELECTRIC THERMAL MANAGEMENT FLUIDS AND METHODS FOR USING THEM CASTROL LTD (GB) 2025-06-04 EP disclosed
US-12016856-B2 Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders ARDELYX, INC. (US) 2024-06-25 US disclosed
US-20240191119-A1 Dielectric Thermal Management Fluids and Methods for Using Them CASTROL LIMITED (GB) 2024-06-13 US disclosed
US-20230241217-A1 HYDROGEL IRRADIATION ASCENDIS PHARMA A/S (DK) 2023-08-03 US disclosed
EP-3534214-B1 PROCESS CARTRIDGE AND IMAGE-FORMING APPARATUS CANON KK (JP) 2022-02-16 EP disclosed
US-10501499-B2 Peptides derived from viral proteins for use as immunogens and dosage reactants BIONOR IMMUNO AS (NO) 2019-12-10 US disclosed
EP-3534215-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2019-09-04 EP disclosed
EP-3534214-A1 PROCESS CARTRIDGE AND IMAGE-FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 2019-09-04 EP disclosed
US-9983456-B2 Light control film HITACHI CHEMICAL COMPANY, LTD. (JP) 2018-05-29 US disclosed
US-9855340-B2 Hydrogel prodrugs ASCENDIS PHARMA A/S (DK) 2018-01-02 US disclosed
US-8681418-B2 Light control film HITACHI CHEMICAL COMPANY, LTD. (JP) 2014-03-25 US disclosed
US-8570642-B2 Light control film HITACHI CHEMICAL COMPANY, LTD. (JP) 2013-10-29 US disclosed
US-8541448-B2 Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders ARDELYX, INC. (US) 2013-09-24 US disclosed
US-20120314276-A1 LIGHT CONTROL FILM GAUZY LTD (IL) 2012-12-13 US disclosed
US-20120307348-A1 LIGHT CONTROL FILM HITACHI CHEMICAL COMPANY, LTD. (JP) 2012-12-06 US disclosed
US-20120263670-A1 COMPOUNDS AND METHODS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS ARDELYX, INC. (US) 2012-10-18 US disclosed
US-8138272-B2 Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds ELAN PHARMACEUTICALS, INC. (US) 2012-03-20 US disclosed
US-20110217546-A1 LIGHT CONTROL FILM GAUZY LTD (IL) 2011-09-08 US disclosed
US-20110143131-A1 LIGHT CONTROL FILM GAUZY LTD (IL) 2011-06-16 US disclosed
US-20080031848-A1 Preparation of Polymer Conjugates of Therapeutic, Agricultural, and Food Additive Compounds ELAN PHARMACEUTICALS, INC. 2008-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080031848-A1 Preparation of Polymer Conjugates of Therapeutic, Agricultural, and Food Additive Compounds PIGO, MANBA, OAT MAPK1 3922/4885ALDH1A1 174/4885TSHR 2205/4885
US-20120263670-A1 COMPOUNDS AND METHODS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS SLC10A1, SLC10A2, FABP2 MAPK1 2602/4885ALDH1A1 1732/4885TSHR 688/4885
US-20230241217-A1 HYDROGEL IRRADIATION H1-0, H1-2, H1-3 MAPK1 3570/4885ALDH1A1 307/4885TSHR 1072/4885
US-10501499-B2 Peptides derived from viral proteins for use as immunogens and dosage reactants HAVCR2, CXCL10, CCL5 MAPK1 2384/4885ALDH1A1 3747/4885TSHR 3610/4885
US-12016856-B2 Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders SLC10A1, SLC10A2, FABP3 MAPK1 2648/4885ALDH1A1 2512/4885TSHR 680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.