Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ITK | Q08881 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539138 | 0.77 | SMN1; SMN2 (0.48) | ALDH1A1 | |
| SCHEMBL7546022 | 0.76 | MAPT (0.41) | ALDH1A1 | |
| SCHEMBL7534511 | 0.76 | ALDH1A1 (0.51) | ALDH1A1 | |
| SCHEMBL7535208 | 0.76 | MAPK1 (0.50) | — | |
| SCHEMBL6068038 | 0.75 | LMNA (0.49) | — | |
| SCHEMBL27586269 | 0.74 | HSD17B10 (0.64) | HSD17B10ITKALDH1A1 | |
| SCHEMBL7247636 | 0.73 | DYRK1A (0.51) | — | |
| SCHEMBL7534938 | 0.73 | LMNA (0.47) | HSD17B10 | |
| SCHEMBL31404204 | 0.72 | PI4KA (0.60) | HSD17B10 | |
| SCHEMBL27034701 | 0.72 | PI4KA (0.60) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254123-A1 | 2-BENZOTHIAZOLYL UREA DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | Abbott GmbH & Co. KG (DE) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001057008-A1 | 2-BENZOTHIAZOLYL UREA DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | ABBOTT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG & COMPANY KOMMANDITGESELLSCHAFT (DE) | 2001-08-09 | — | — | WO | disclosed |