Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262688 | 0.79 | PHF8 (0.44) | ALDH1A1SMN1; SMN2TSHRMAPTKDM4E | |
| SCHEMBL23230291 | 0.78 | MEN1 (0.32) | ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL3200403 | 0.77 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2TSHRMAPTKDM4E | |
| SCHEMBL754536 | 0.77 | PAOX (0.37) | ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL3989151 | 0.76 | LMNA (0.50) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6331887 | 0.76 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL755507 | 0.75 | TSHR (0.35) | ALDH1A1KMT2AMEN1TSHRKDM4E | |
| SCHEMBL3260234 | 0.75 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2TSHRMAPTFAAH | |
| SCHEMBL3260974 | 0.75 | FAAH (0.33) | SMN1; SMN2TSHRMAPTFAAH | |
| SCHEMBL3260225 | 0.75 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2TSHRMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |