Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 8/20 | 0.34 |
| ▸ | NPC1 | O15118 | 7/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8509620 | 0.86 | NPC1 (0.38) | RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL15655546 | 0.79 | ENPP2 (0.39) | RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL15655562 | 0.75 | SMYD3 (0.38) | RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2324598 | 0.74 | CHRM1 (0.35) | RAB9ANPC1 | |
| SCHEMBL17438421 | 0.72 | ALDH1A1 (0.56) | NAAASMN1; SMN2ALDH1A1 | |
| SCHEMBL19015180 | 0.72 | ALDH1A1 (0.56) | NAAASMN1; SMN2ALDH1A1 | |
| SCHEMBL17438422 | 0.72 | ALDH1A1 (0.56) | NAAASMN1; SMN2ALDH1A1 | |
| SCHEMBL15748998 | 0.72 | ALDH1A1 (0.56) | NAAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8512944 | 0.71 | RAB9A (0.38) | RAB9ANPC1ALDH1A1 | |
| SCHEMBL753832 | 0.71 | HDAC3 (0.41) | RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2429998-A1 | 5-MEMBERED HETEROCYCLIC COMPOUND CYCLOPENTA[C]PYRROLYLALKYLCARBAMATE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010130943-A1 | 5-MEMBERED HETEROCYCLIC COMPOUND CYCLOPENTA[C]PYRROLYLALKYLCARBAMATE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-11-18 | — | — | WO | disclosed |