SCHEMBL754546

SCHEMBL754546

CCCCN(CCCC)C(O)CCOCCC(O)N(CCCC)CCCC

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
HTT P42858 2/20 0.33
SPHK1 Q9NYA1 1/20 0.33
USP2 O75604 1/20 0.33
MEN1 O00255 1/20 0.33
THRB P10828 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.33
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
MMP8 P22894 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL5497205 0.91 GPR84 (0.35) MMP1MMP2MMP3MMP8
SCHEMBL976818 0.82 MMP1 (0.35) SPHK1MMP1MMP2MMP3MMP8
SCHEMBL1548681 0.82 ALDH1A1 (0.36) SPHK1MMP1MMP2MMP3MMP8
SCHEMBL19305047 0.82 HTT (0.52) TSHRHTTSPHK1USP2MEN1
SCHEMBL10601926 0.80 GPR84 (0.40) HTTSPHK1MAPT
SCHEMBL11867698 0.80 ALDH1A1 (0.52) TSHRMMP1MMP2MMP3MMP8
SCHEMBL10794262 0.78 ALDH1A1 (0.38) TSHRHTTSPHK1MEN1KMT2A
SCHEMBL1966027 0.78 GPR84 (0.43) HTTSPHK1MAPT
SCHEMBL11802193 0.78 GPR84 (0.43) HTTSPHK1MAPT
SCHEMBL4937300 0.76 DNM1 (0.44) SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200054486-A1 BIODEGRADABLE INTRAVITREAL IMPLANTS DUTTA TATHAGATA (IN) 2020-02-20 US claimed
WO-2019198923-A1 MICROSTRUCTURE FOR TRANSCUTANEOUS AND INTRACUTANEOUS DRUG DELIVERY OF CYCLOSPORIN A (CSA) 가천대학교 산학협력단 2019-10-17 WO claimed
WO-2019008592-A1 BIODEGRADABLE INTRAVITREAL IMPLANTS DUTTA TATHAGATA (IN) 2019-01-10 WO claimed
EP-2737923-B1 Electrode with integrated microneedles for introducing genetic material and a method for its preparation RAPHAS CO LTD (KR) 2016-09-14 EP claimed
EP-2737923-A2 ELECTRO-MICRONEEDLE INTEGRATED BODY FOR IN-SITU CUTANEOUS GENE TRANSFER AND METHOD OF MANUFACTURING SAME Raphas Co., Ltd. (KR) 2014-06-04 EP claimed
US-20140142492-A1 ELECTRO-MICRONEEDLE INTEGRATED BODY FOR IN-SITU CUTANEOUS GENE TRANSFER AND METHOD OF MANUFACTURING SAME Industry-Acadmic Cooperation Foundation, Yonsei Univ. (KR) 2014-05-22 US claimed
EP-1602334-A2 Apparatus for delivery of a therapeutic agent to aneurysmal tissue Medtronic Vascular, Inc. (US) 2005-12-07 EP claimed
US-20050266043-A1 Methods and compounds for treatment of aneurysmal tissue MEDTRONIC VASCULAR, INC. (US) 2005-12-01 US claimed
US-20050266042-A1 Methods and apparatus for treatment of aneurysmal tissue MEDTRONIC VASCULAR, INC. (US) 2005-12-01 US claimed
EP-1600181-A2 Methods and compounds for treatment of aneurysmal tissue Medtronic Vascular, Inc. (US) 2005-11-30 EP claimed
US-20050043786-A1 Methods and apparatus for treatment of aneurysmal tissue MEDTRONIC AVE, INC. 2005-02-24 US claimed
EP-1508314-A1 Methods and apparatus for treatment of aneurysmal tissue Medtronic Vascular, Inc. (US) 2005-02-23 EP claimed
US-6506410-B1 Sustained release microparticle and method for preparing the same KONG KOOK PHARMACEUTICAL CO., LTD. (KR) 2003-01-14 US claimed
WO-1989003678-A1 LOW RESIDUAL SOLVENT MICROSPHERES AND MICROENCAPSULATION PROCESS STOLLE RESEARCH & DEVELOPMENT CORPORATION (US) 1989-05-05 WO claimed
US-4389330-A Microencapsulation process STOLLE RESEARCH AND DEVELOPMENT CORPORATION (US) 1983-06-21 US claimed
WO-2022075771-A1 DRUG-DELIVERY STENT, MANUFACTURING METHOD THEREOF, AND DRUG DELIVERY METHOD USING SAME 연세대학교 산학협력단 2022-04-14 WO disclosed
US-10617313-B2 Pressure catheter device CLINICAL INNOVATIONS, LLC (US) 2020-04-14 US disclosed
EP-0264106-A2 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use Banyu Pharmaceutical Co., Ltd. (JP) 1988-04-20 EP disclosed
US-4713245-A HEAT TREATMENT FORMS PROTECTIVE COATING DISSOLVING IN ACIDIC CONDITIONS MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1987-12-15 US disclosed
US-4389330-A Microencapsulation process STOLLE RESEARCH AND DEVELOPMENT CORPORATION (US) 1983-06-21 US disclosed