Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758728 | 0.86 | MAPT (0.46) | HTTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL15641224 | 0.84 | MAPT (0.45) | HTTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1758939 | 0.83 | TSHR (0.54) | HTTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL29337714 | 0.81 | HTT (0.47) | CYP3A4HTTMEN1KMT2AMAPT | |
| SCHEMBL13361795 | 0.80 | PKM (0.52) | HTTMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL2914417 | 0.78 | TSHR (0.46) | HTTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL21179834 | 0.78 | HTT (0.43) | CYP3A4HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1750408 | 0.77 | TSHR (0.50) | CYP3A4HTTMEN1KMT2ALMNA | |
| SCHEMBL27951772 | 0.77 | ADRB2 (0.43) | HTTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL22060057 | 0.76 | EPHX2 (0.63) | HTTMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9743667-B2 | Substituted benzene fungicides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-08-29 | — | — | US | disclosed |
| EP-2430921-B1 | Substituted benzene fungicides | DU PONT (US) | 2017-07-05 | — | — | EP | disclosed |
| US-9198433-B2 | Substituted benzene fungicides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-12-01 | — | — | US | disclosed |
| US-20150335023-A1 | SUBSTITUTED BENZENE FUNGICIDES | FMC CORPORATION | 2015-11-26 | — | — | US | disclosed |
| US-20140323436-A1 | SUBSTITUTED BENZENE FUNGICIDES | FMC CORPORATION | 2014-10-30 | — | — | US | disclosed |
| US-8822521-B2 | Substituted benzene fungicides | E I DU PONT DE NEMOURS AND COMPANY (DE) | 2014-09-02 | — | — | US | disclosed |
| EP-2129225-B1 | SUBSTITUTED BENZENE FUNGICIDES | DU PONT (US) | 2012-12-05 | — | — | EP | disclosed |
| EP-2430921-A2 | Substituted benzene fungicides | E.I. Du Pont De Nemours And Company (US) | 2012-03-21 | — | — | EP | disclosed |
| US-20100120714-A1 | SUBSTITUTED BENZENE FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-05-13 | — | — | US | disclosed |
| EP-2129225-A2 | SUBSTITUTED BENZENE FUNGICIDES | E. I. Du Pont de Nemours and Company (US) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008124092-A2 | SUBSTITUTED BENZENE FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150335023-A1 | SUBSTITUTED BENZENE FUNGICIDES | NR0B1, CBR3, NR0B2 | CYP3A4 323/4885HTT 4274/4885MEN1 2998/4885 |
| US-20140323436-A1 | SUBSTITUTED BENZENE FUNGICIDES | NR0B1, CBR3, NR0B2 | CYP3A4 323/4885HTT 4274/4885MEN1 2998/4885 |
| US-20100120714-A1 | SUBSTITUTED BENZENE FUNGICIDES | NR0B1, CBR3, NR0B2 | CYP3A4 363/4885HTT 4296/4885MEN1 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.