Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 4/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.37 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 2/20 | 0.34 |
| ▸ | KDM5A | P29375 | 2/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.31 |
| ▸ | BRS3 | P32247 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810513 | 0.81 | NR3C2 (0.43) | NR3C2CSNK1A1CSNK1DCSNK1G2GSK3B | |
| SCHEMBL751850 | 0.79 | BRS3 (0.36) | CSNK1A1CSNK1DCSNK1G2BRS3MAPK14 | |
| SCHEMBL756226 | 0.70 | NR3C2 (0.42) | NR3C2CSNK1DDAOKDM5AKDM5B | |
| SCHEMBL754583 | 0.68 | NR3C2 (0.40) | NR3C2DAOKDM5AKDM5BPTGS1 | |
| SCHEMBL754151 | 0.63 | NR3C2 (0.51) | NR3C2PTGS1PTGS2AOC3 | |
| SCHEMBL6127541 | 0.58 | NR3C2 (1.00) | NR3C2 | |
| SCHEMBL30309267 | 0.57 | LOXL2 (0.48) | — | |
| SCHEMBL16749598 | 0.57 | LOXL2 (0.48) | — | |
| SCHEMBL17981865 | 0.57 | MAOB (0.53) | NR3C2SCN9A | |
| SCHEMBL20449105 | 0.57 | RAB9A (0.41) | KDM5AKDM5BMAPKAPK2BRS3KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |