SCHEMBL754583

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL756226	0.85	NR3C2 (0.42)	NR3C2KDM5AKDM5BPTGS1PTGS2
	SCHEMBL755033	0.85	CSNK1A1 (0.33)	PTGS1PTGS2KCNH2TMEM97SIGMAR1
	SCHEMBL754752	0.81	USP1 (0.36)	PTGS1PTGS2IDH1KCNH2TMEM97
	SCHEMBL755617	0.78	TRPA1 (0.30)	—
	SCHEMBL754532	0.78	JAK2 (0.43)	KCNH2LIPGELOVL1
	SCHEMBL751851	0.78	CYP11B1 (0.32)	IDH1LIPGKDM4CALDH1A1
	SCHEMBL754375	0.77	FYN (0.33)	IDH1LIPGALDH1A1
	SCHEMBL754533	0.77	SMN1; SMN2 (0.34)	PTGS1PTGS2IDH1KCNH2TMEM97
	SCHEMBL752929	0.74	CYP4F2 (0.44)	LIPG
	SCHEMBL749812	0.74	NPSR1 (0.33)	IDH1LIPGKDM4CALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.