SCHEMBL754532

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL752783	0.90	ACACB (0.38)	JAK2JAK3GRM5LMNATSHR
	SCHEMBL753011	0.86	JAK2 (0.45)	JAK2JAK3ELOVL1GRM5KDM4E
	SCHEMBL751416	0.85	JAK2 (0.44)	JAK2JAK3ELOVL1GRM5KDM4E
	SCHEMBL752324	0.84	GPR84 (0.37)	MAOBACACBKCNH2
	SCHEMBL756220	0.84	JAK2 (0.43)	JAK2JAK3ELOVL1GRM5KDM4E
	SCHEMBL755294	0.83	MRGPRX4 (0.33)	GRM5KDM4ETDP1ACACB
	SCHEMBL755319	0.82	JAK2 (0.43)	JAK2JAK3ELOVL1GRM5KDM4E
	SCHEMBL755033	0.82	CSNK1A1 (0.33)	ELOVL1KCNH2
	SCHEMBL754587	0.82	JAK2 (0.41)	JAK2JAK3ELOVL1GRM5KDM4E
	SCHEMBL755617	0.82	TRPA1 (0.30)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.