SCHEMBL815121

SCHEMBL815121

CCn1cc(C(=O)O)c(=O)[nH]c1=S

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM3B Q7LBC6 2/20 0.42
KMT2A Q03164 4/20 0.40
LMNA P02545 4/20 0.40
MEN1 O00255 2/20 0.40
ABCC4 O15439 1/20 0.40
PKM P14618 1/20 0.40
PTGS1 P23219 1/20 0.40
CYP2C9 P11712 2/20 0.40
DDO Q99489 1/20 0.40
MAPT P10636 1/20 0.40
CYP1A2 P05177 4/20 0.39
CYP2C19 P33261 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
GAA P10253 2/20 0.39
KDM4E B2RXH2 5/20 0.39
HPGD P15428 4/20 0.39
HSD17B10 Q99714 4/20 0.39
ALDH1A1 P00352 4/20 0.39
TSHR P16473 3/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10823650 0.83 KMT2A (0.53) KMT2ALMNAMEN1ABCC4PKM
SCHEMBL9054601 0.83 KDM3B (0.39) KDM3BKMT2ALMNAMEN1ABCC4
SCHEMBL7545848 0.77 KDM3B (0.46) KDM3BKMT2ACYP2C9DDOMAPT
SCHEMBL24205178 0.75 MAPK1 (0.45) HPGDALDH1A1NPSR1
SCHEMBL11239615 0.71 CYP2C19 (0.69) KDM3BKMT2ALMNAMEN1CYP2C9
SCHEMBL31282172 0.69 KMT2A (0.49) KMT2ALMNAMEN1CYP2C9DDO
SCHEMBL11246068 0.69 CYP2C19 (0.79) KDM3BKMT2AMEN1CYP2C9MAPT
SCHEMBL11238675 0.69 CYP2C19 (0.79) KDM3BKMT2AMEN1CYP2C9MAPT
SCHEMBL425895 0.69 KMT2A (0.49) KMT2AMEN1CYP2C9DDOMAPT
SCHEMBL10823643 0.69 HTT (0.56) KMT2AMEN1CYP2C9DDOMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2199052-B1 PROCESS FOR PRODUCTION OF INJECTION-MOLDED ARTICLE OF POLYLACTIC ACID RESIN KAO CORP (JP) 2014-01-22 EP disclosed
US-8062574-B2 Process for production of injection-molded article of polylactic acid resin KAO CORPORATION (JP) 2011-11-22 US disclosed
US-20100201037-A1 PROCESS FOR PRODUCTION OF INJECTION-MOLDED ARTICLE OF POLYLACTIC ACID RESIN KAO CORPORATION (JP) 2010-08-12 US disclosed
EP-2199052-A1 PROCESS FOR PRODUCTION OF INJECTION-MOLDED ARTICLE OF POLYLACTIC ACID RESIN Kao Corporation (JP) 2010-06-23 EP disclosed