Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537772 | 0.94 | LMNA (0.71) | L3MBTL1LMNAALDH1A1KMT2AOPRK1 | |
| SCHEMBL4274767 | 0.88 | L3MBTL1 (0.68) | L3MBTL1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL13649145 | 0.87 | KMT2A (0.60) | L3MBTL1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL12642622 | 0.87 | KMT2A (0.60) | L3MBTL1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL3595934 | 0.86 | KMT2A (0.78) | L3MBTL1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL1886766 | 0.86 | KMT2A (0.78) | L3MBTL1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL15249477 | 0.86 | KMT2A (0.78) | L3MBTL1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL16250460 | 0.86 | KMT2A (0.78) | L3MBTL1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL3595931 | 0.86 | KMT2A (0.78) | L3MBTL1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL3589020 | 0.84 | LMNA (0.81) | L3MBTL1LMNAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254123-A1 | 2-BENZOTHIAZOLYL UREA DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | Abbott GmbH & Co. KG (DE) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001057008-A1 | 2-BENZOTHIAZOLYL UREA DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | ABBOTT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG & COMPANY KOMMANDITGESELLSCHAFT (DE) | 2001-08-09 | — | — | WO | disclosed |