Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | YAP1 | P46937 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546012 | 1.00 | ITGB3 (0.61) | ITGB3ITGA2BPTPN1CACNA1BACE | |
| SCHEMBL3997218 | 0.99 | ITGB3 (0.62) | ITGB3ITGA2BPTPN1CACNA1BACE | |
| SCHEMBL3500202 | 0.91 | CACNA1B (0.56) | ITGB3ITGA2BPTPN1CACNA1BYAP1 | |
| SCHEMBL3500200 | 0.91 | CACNA1B (0.56) | ITGB3ITGA2BPTPN1CACNA1BYAP1 | |
| SCHEMBL3498976 | 0.85 | YAP1 (0.53) | ITGB3ITGA2BPTPN1CACNA1BYAP1 | |
| SCHEMBL3498974 | 0.85 | YAP1 (0.53) | ITGB3ITGA2BPTPN1CACNA1BYAP1 | |
| SCHEMBL10349337 | 0.84 | ITGB3 (0.59) | ITGB3ITGA2BPTPN1CACNA1BACE | |
| SCHEMBL13383892 | 0.83 | KDM4A (0.54) | ITGB3ITGA2BACE | |
| SCHEMBL5048350 | 0.83 | CTSS (0.55) | ITGB3ITGA2BPTPN1CACNA1BACE | |
| SCHEMBL7228964 | 0.82 | ACE (0.55) | ITGB3ITGA2BACEATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |