Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 11/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 11/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540848 | 0.91 | MEN1 (0.44) | MEN1KMT2AFOLH1ITGB1ITGA4 | |
| SCHEMBL7540844 | 0.91 | MEN1 (0.44) | MEN1KMT2AFOLH1ITGB1ITGA4 | |
| SCHEMBL7540570 | 0.89 | ITGB1 (0.54) | FOLH1ITGB1ITGA4MAPTMMP3 | |
| SCHEMBL7546168 | 0.89 | ITGB1 (0.54) | FOLH1ITGB1ITGA4MAPTMMP3 | |
| SCHEMBL7548271 | 0.88 | FOLH1 (0.51) | FOLH1ITGB1ITGA4MAPTMMP3 | |
| SCHEMBL7545880 | 0.87 | FPR2 (0.55) | KMT2AFOLH1ITGB1ITGA4MAPT | |
| SCHEMBL7545943 | 0.86 | FOLH1 (0.48) | MEN1KMT2AFOLH1MAPTMMP3 | |
| SCHEMBL7543834 | 0.84 | MMP3 (0.46) | ITGB1ITGA4CTSLMMP3MMP2 | |
| SCHEMBL7543837 | 0.84 | MMP3 (0.46) | ITGB1ITGA4CTSLMMP3MMP2 | |
| SCHEMBL7547281 | 0.83 | FOLH1 (0.46) | FOLH1MAPTCTSLMMP3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |