Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MYOC | Q99972 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | FCER2 | P06734 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7542518 | 0.91 | MMP1 (0.39) | FOLH1MAPTCA2MMP1FCER2 | |
| SCHEMBL7542526 | 0.91 | MMP1 (0.39) | FOLH1MAPTCA2MMP1FCER2 | |
| SCHEMBL7538785 | 0.89 | FOLH1 (0.54) | FOLH1MAPTMMP3MMP2ACE | |
| SCHEMBL7541870 | 0.89 | FOLH1 (0.54) | FOLH1MAPTMMP3MMP2ACE | |
| SCHEMBL7543615 | 0.89 | ACE (0.40) | FOLH1MAPTCA2MMP1FCER2 | |
| SCHEMBL7547257 | 0.88 | FOLH1 (0.55) | FOLH1MAPTMMP3MMP2ACE | |
| SCHEMBL7546158 | 0.88 | FOLH1 (0.53) | FOLH1MAPTMMP3MMP2ACE | |
| SCHEMBL7547307 | 0.87 | FOLH1 (0.52) | FOLH1MAPTMMP3MMP2ACE | |
| SCHEMBL7546261 | 0.86 | MEN1 (0.48) | FOLH1MAPTMEN1KMT2AMMP3 | |
| SCHEMBL7544917 | 0.85 | FPR2 (0.56) | FOLH1MEN1KMT2AMMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |