Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 12/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 12/20 | 0.54 |
| ▸ | MMP3 | P08254 | 4/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540570 | 1.00 | ITGB1 (0.54) | ITGB1ITGA4MMP3FOLH1MMP2 | |
| SCHEMBL7548271 | 0.93 | FOLH1 (0.51) | ITGB1ITGA4MMP3FOLH1MMP2 | |
| SCHEMBL7545100 | 0.93 | ITGB1 (0.51) | ITGB1ITGA4MMP3MMP2MAPT | |
| SCHEMBL7538353 | 0.93 | MMP3 (0.51) | ITGB1ITGA4MMP3MMP2MAPT | |
| SCHEMBL7545880 | 0.92 | FPR2 (0.55) | ITGB1ITGA4MMP3FOLH1MMP2 | |
| SCHEMBL7546261 | 0.89 | MEN1 (0.48) | ITGB1ITGA4MMP3FOLH1MMP2 | |
| SCHEMBL7539261 | 0.88 | MMP3 (0.47) | ITGB1ITGA4MMP3MMP2MME | |
| SCHEMBL7543837 | 0.87 | MMP3 (0.46) | ITGB1ITGA4MMP3MMP2MME | |
| SCHEMBL7543834 | 0.87 | MMP3 (0.46) | ITGB1ITGA4MMP3MMP2MME | |
| SCHEMBL7538645 | 0.87 | ITGB1 (0.52) | ITGB1ITGA4MMP3MMP2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |