Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12443641 | 0.82 | MAPT (0.69) | PTGS2MAPTLMNATP53ALDH1A1 | |
| SCHEMBL8352712 | 0.81 | LMNA (0.71) | PTGS2MAPTLMNATP53ALDH1A1 | |
| SCHEMBL19857277 | 0.79 | MAPT (0.56) | PTGS2MAPTLMNATP53ALDH1A1 | |
| SCHEMBL15790775 | 0.74 | LMNA (0.54) | PTGS2MAPTLMNATP53ALDH1A1 | |
| SCHEMBL17708398 | 0.72 | MAPT (1.00) | PTGS2MAPTLMNATP53ALDH1A1 | |
| SCHEMBL8048128 | 0.71 | ALDH1A1 (0.49) | PTGS2MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8351721 | 0.71 | ALDH1A1 (0.57) | PTGS2MAPTLMNATP53ALDH1A1 | |
| SCHEMBL7396129 | 0.70 | ALDH1A1 (0.57) | PTGS2MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL30580665 | 0.70 | OXTR (0.47) | PTGS2LMNAALDH1A1RAB9APTGS1 | |
| SCHEMBL21467805 | 0.70 | ALDH1A1 (1.00) | PTGS2MAPTLMNATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150972-A1 | TRIAZOLE AND TETRAZOLE DERIVATIVES, AND THEIR THERAPEUTIC USE | SANOFI-SYNTHELABO (FR) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000046220-A1 | TRIAZOLE AND TETRAZOLE DERIVATIVES, AND THEIR THERAPEUTIC USE | SANOFI-SYNTHELABO (FR) | 2000-08-10 | — | — | WO | disclosed |