Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438530 | 0.82 | SMN1; SMN2 (0.67) | ALDH1A1HPGDHTTPOLBSMN1; SMN2 | |
| SCHEMBL6930563 | 0.81 | ALDH1A1 (0.67) | ALDH1A1HPGDHTTPOLBSMN1; SMN2 | |
| SCHEMBL15790775 | 0.76 | LMNA (0.54) | ALDH1A1HPGDHTTSMN1; SMN2MAPT | |
| SCHEMBL24038505 | 0.73 | SMN1; SMN2 (0.60) | ALDH1A1HPGDHTTPOLBSMN1; SMN2 | |
| SCHEMBL8048128 | 0.72 | ALDH1A1 (0.49) | ALDH1A1HTTPOLBSMN1; SMN2MAPT | |
| SCHEMBL8351721 | 0.72 | ALDH1A1 (0.57) | ALDH1A1HPGDHTTSMN1; SMN2MAPT | |
| SCHEMBL10664251 | 0.71 | SMN1; SMN2 (0.70) | ALDH1A1HPGDHTTPOLBSMN1; SMN2 | |
| SCHEMBL15337450 | 0.71 | SMN1; SMN2 (0.70) | ALDH1A1HPGDHTTPOLBSMN1; SMN2 | |
| SCHEMBL5213845 | 0.70 | ALDH1A1 (0.52) | ALDH1A1HPGDHTTPOLBSMN1; SMN2 | |
| SCHEMBL7546978 | 0.70 | PTGS2 (0.62) | ALDH1A1HPGDHTTSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150972-A1 | TRIAZOLE AND TETRAZOLE DERIVATIVES, AND THEIR THERAPEUTIC USE | SANOFI-SYNTHELABO (FR) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000046220-A1 | TRIAZOLE AND TETRAZOLE DERIVATIVES, AND THEIR THERAPEUTIC USE | SANOFI-SYNTHELABO (FR) | 2000-08-10 | — | — | WO | disclosed |