Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 6/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804801 | 0.85 | RECQL (0.46) | RECQLL3MBTL1JAK2TYK2ALDH1A1 | |
| SCHEMBL8800986 | 0.79 | RECQL (0.48) | RECQLJAK2TYK2CDK2MAPK1 | |
| SCHEMBL7544426 | 0.78 | HPGD (0.42) | MAPK13MAPK12KDM4EMAPTALDH1A1 | |
| SCHEMBL7548664 | 0.77 | KEAP1 (0.36) | RECQLROCK2PRKD3MAP4K4LCK | |
| SCHEMBL7549213 | 0.77 | L3MBTL1 (0.41) | RECQLL3MBTL1JAK2MAPK13KDR | |
| SCHEMBL8805528 | 0.77 | MAPK14 (0.40) | RECQLL3MBTL1JAK2CDC7PLK4 | |
| SCHEMBL7549390 | 0.77 | ALDH1A1 (0.50) | CYP3A4JAK2TYK2CDK2ALDH1A1 | |
| SCHEMBL8799820 | 0.75 | ALDH1A1 (0.40) | KCNH2L3MBTL1MAPK13PRKCIMAPK12 | |
| SCHEMBL7546071 | 0.74 | FLT1 (0.40) | L3MBTL1JAK2MAPK13MAPK1KDR | |
| SCHEMBL7547513 | 0.74 | KMT2A (0.53) | CYP3A4MAPK1KDRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049708-A9 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | — | 1998-05-22 | — | — | WO | disclosed |
| WO-1996022295-A9 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | — | 1996-11-14 | — | — | WO | disclosed |