SCHEMBL754737

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL752233	0.87	MAPT (0.48)	ALDH1A1LMNAKDM4EHPGDPOLB
	SCHEMBL753088	0.86	POLB (0.38)	ALDH1A1LMNAPOLBMMP3MMP12
	SCHEMBL752163	0.86	LMNA (0.48)	ALDH1A1LMNAKDM4EHPGDPOLB
	Dimethylamine SCHEMBL752802	0.85	CNR2 (0.38)	ALDH1A1LMNAPOLBMMP3MMP12
	SCHEMBL755706	0.85	MMP3 (0.41)	ALDH1A1LMNAKDM4EHPGDPOLB
	Benzylamine SCHEMBL754738	0.85	POLB (0.38)	ALDH1A1LMNAKDM4EPOLBTP53
	SCHEMBL755785	0.85	ALDH1A1 (0.39)	ALDH1A1LMNAKDM4EHPGDPOLB
	Aniline SCHEMBL752234	0.84	ALDH1A1 (0.38)	ALDH1A1LMNAKDM4EPOLBMMP3
	SCHEMBL754998	0.83	KMT2A (0.42)	ALDH1A1LMNAHPGDPOLBMMP3
	Methylamine SCHEMBL753441	0.83	CNR2 (0.38)	ALDH1A1KDM4EPOLBMMP3MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.