Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | RORB | Q92753 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1643690 | 0.81 | RECQL (0.49) | RECQLKMT2AMAPK14RORBCES2 | |
| SCHEMBL8800986 | 0.79 | RECQL (0.48) | RECQLKMT2AMAPK14RORBCES2 | |
| SCHEMBL1643526 | 0.78 | RORB (0.51) | RECQLKMT2AMAPK14RORBCES2 | |
| SCHEMBL1643623 | 0.78 | MAPK14 (0.53) | RECQLKMT2AMAPK14RORBCES2 | |
| SCHEMBL7548003 | 0.78 | SHBG (0.44) | KMT2AALDH1A1GAAKDM4EMAPK1 | |
| SCHEMBL1643090 | 0.74 | RORB (0.47) | RECQLKMT2AMAPK14RORBRORC | |
| SCHEMBL1642370 | 0.74 | MAPK14 (0.46) | RECQLKMT2AMAPK14RORBALDH1A1 | |
| SCHEMBL7548594 | 0.73 | RECQL (0.48) | RECQLKMT2AMAPK14RORBCES2 | |
| SCHEMBL6669054 | 0.73 | NAPRT (0.58) | RECQLKMT2AMAPK14RORBCES2 | |
| SCHEMBL50416 | 0.73 | CES2 (0.71) | RECQLKMT2AMAPK14RORBCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049708-A9 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | — | 1998-05-22 | — | — | WO | disclosed |