Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799386 | 0.82 | SHBG (0.44) | SHBGPKMCASP3SENP8SENP7 | |
| SCHEMBL7547464 | 0.78 | RECQL (0.48) | PKMKMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL8805065 | 0.76 | SHBG (0.44) | SHBGPKMCASP3SENP8SENP7 | |
| SCHEMBL8984576 | 0.71 | SHBG (0.59) | SHBGPKMKMT2AALDH1A1KDM4E | |
| SCHEMBL8956742 | 0.69 | SHBG (0.54) | SHBGPKMKMT2AALDH1A1CTBP2 | |
| SCHEMBL7546276 | 0.68 | MEN1 (0.45) | SHBGKMT2AALDH1A1KDM4ECTBP2 | |
| SCHEMBL27917766 | 0.66 | SHBG (0.54) | SHBGPKMALDH1A1KDM4ECTBP2 | |
| SCHEMBL31201903 | 0.66 | CYP3A4 (0.53) | SHBGPKMKMT2AALDH1A1CTBP2 | |
| SCHEMBL286906 | 0.66 | CTBP2 (0.56) | SHBGPKMCASP3KMT2AALDH1A1 | |
| SCHEMBL29810302 | 0.66 | CTBP2 (0.56) | SHBGPKMCASP3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049708-A9 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | — | 1998-05-22 | — | — | WO | disclosed |